How to Fix Outlook Mail Not Opening How to Fix Outlook Mail Not Opening If Outlook is not opening in Chrome get help 1-888-653-7618 tollfree try clearing your cache and cookies, using an incognito window to rule out extensions, or disabling all extensions to find a conflict. ​​​​​​​If the issue is with links from the desktop Outlook client opening in the wrong browser, check your Outlook settings to ensure hyperlinks are set to open in the "Default browser" and that Chrome is set as your Windows default browser. Troubleshoot Chrome-specific issues https://hackmd.io/@bhectorblog/fix-outlook-mail-not-opening-in-browsers